Bone Marrow Biopsy Procedure. Pt is usually given some sedation and some local
anesthetic medicine.
After the Bone Marrow Procedure a Small Band Aid is left on the patient. Why is a Bone Marrow Done?
Examination of the bone marrow is the most
valuable diagnostic test to evaluate hematologic disorders. Bone marrow aspiration and biopsy
also is used to stage lymphoproliferative disorders and for prognostic purposes in chronic lymphoproliferative disorders such as chronic lymphatic leukemia.
Bone marrow aspiration
and biopsy also is useful in the diagnostic workup of fever of unknown origin (FUO). It may reveal
infections, such as tuberculosis, Mycobacterium avium-intracellulare (MAI) infections,
histoplasmosis, leishmaniasis, and other disseminated fungal infections. It may be useful in
establishing the diagnosis of storage diseases, such as Niemann-Pick disease and Gaucher disease. Finally, it can be a valuable tool in diagnosing metastatic nonhemopoietic malignancies that have spread to the bone marrow when all other imaging and diagnostic
modalities have failed or when a leucoerythroblastic peripheral blood picture is
present.
Bone Marrow Biopsy
Technique Proper technique is required to
obtain an adequate sample and a suitable specimen for processing.
The pathology request
should contain all the pertinent clinical information and laboratory data. Obtaining informed
consent and providing information regarding the procedure will minimize any apprehension that
the patient may have, as will talking to the patient during each step of the bone marrow aspiration
and biopsy.
Bone Marrow Biopsy
Complications Complications from a bone
marrow aspiration and biopsy include infection and bleeding. With proper sterile atraumatic
technique these complications are rare.
Absolute contraindications to performing the procedure
include hemophilia or related coagulation disorders and infection involving the biopsy area. Thrombocytopenia is not a contraindication, but take care to avoid trauma that is more
significant than usual.
Another very rare complication from the procedure is cardiac injury after a
sternal bone marrow aspiration, which can be prevented with good technique and by using the guard provided with the bone marrow aspiration needle to avoid deep penetration.
Biopsies never should be obtained from the sternum; only aspiration is performed in that area. Iliac
bone perforation and hemorrhage may occur because of improper technique and patient
positioning.
Chronic pain at the site of the bone marrow aspiration and biopsy is very
rare.
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